The Candidate will contribute to our recombinant antibody discovery and developments related activities using antibody phage display technology.
- Responsible for using antibody phage display platform for discovering antibodies. Reformat recombinant antibodies into other isotypes, species and conformations like bi-specific, and other multi-specific formats.
- Expression and purification of antibodies in bacterial and mammalian system, their characterization and application specific validation.
- Efficiently analyse, record and report data; experience with electronic notebook will be an added advantage
- Prepare presentations, project reports and present in weekly and/or monthly group meetings.
- Actively participate in non-technical activities required for smooth functioning of the department.
Skills Required
- Experienced in Basic molecular and protein biology techniques like DNA manipulation and analysis, plasmid extraction, cloning, PCR; Protein Estimation Methods, SDS PAGE, Western Blotting, ELISA etc.
- Microbial (bacteria / yeast) expression and purification of recombinant proteins
- Mammalian expression and small scale purification of antibodies and/or recombinant proteins
- Prior experience in Phage display technology will be given preference.
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